Resveratrol is an all natural supplement with some of the highest level anti-oxidants on the market. It is commonly found in Red Wine through grape pulp. Rich molecules provide a natural detoxification of muscle and fat tissue that are caused by years of build up due to airborn and terrestrial toxins. By consuming a safe daily dose of Resveratrol, you can start the break down process which will naturally help shed pounds and trim fatty areas.
Studies at Harvard Medical School and the Institute of Genetics and Molecular Biology have found that resveratrol, a natural compound found in several plants and the skin of red grapes , may radically reduce the risk not only of heart disease but also of age related illnesses such as Alzheimer's disease. It might also counter the effects of a high-fat diet and even prolong life.
Resveratrol has the ability to prevent the first step that occurs when estrogen starts the proces that leads to cancer. Scientists believe that this could stop the whole progression that leads to breast cancer down the road. This is dramatic because it was able to be done with fairly low concentrations of reveratrol.
"Now, scientists across the country have identified a substance in red wine called resveratrol that they believe might do more than just protect the heart, but could – in very high concentrations – significantly extend life by preventing a number of age related illnesses."
-Resveratrol may prolong life and fight age-related diseases. Resveratrol is one of a group of antioxidant compounds called polyphenols found in red wine that has been reported to have anti-inflammatory as well as anticancer properties. Resveratrol, may counter type 2 diabetes and insulin resistance, a new study shows.
-This research, funded in part by the National Institute on Aging, was published in the journals, Nature and Cell in November. Dr. Brent Bauer, Director of Internal Medicine’s Complimentary and Integrative Medicine Program at Mayo Clinic says “This may be the best thing since sliced bread for human beings, but we just don’t know yet.
Some people are asking if a resvertarol regimen may contribute to weight loss. Despite misleading statements by some companies, the answer is: unlikely. Resveratrol is not a diet pill, nor is it a miracle pill that will cause weight loss, or remove wrinkles. A long term resveratrol regimen may contribute to healthier living, and healthier individuals look better. Resveratrol mimics the results of a CR diet and could reduce or eliminate a variety of diseases.
Calorie restriction (CR) is a dietary regimen thought to improve health and slow the aging process in animals and humans by limiting dietary energy intake. A CR diet is a dietary intervention which has been documented to increase maximum lifespan and eliminate a variety of diseases. Research at Harvard University found that resveratrol mimics a CR diet in animals and extends their life by 20%-40%. Just like a CR diet, resveratrol may reduce or eliminate a variety of ailments such as heart disease, diabetes, cancer and joint disease. It may also lead to improved athletic endurance and extended human lifespan.
Low Dose Resveratrol May Slow Aging in Mice
Resveratrol is a polyphenolic antioxidant that naturally occurs in plants, including grape skins, and therefore occurs in varying levels in red wine. Resveratrol has made a lot of news in the past few years as researchers have linked it to a variety of health benefits. Resveratrol has been cited as a possible explanation for the "French Paradox," which is that in certain regions of France diets are high in saturated fat (and red wine), but the rate of heart disease is very low. Other benefits attributed to Resveratrol include its potential as an anti-inflammatory, potential as an anti-cancer agent, and most famously, its potential for extending life. A 2006 study found a 40% increase in the life expectancy of lab mice fed very high levels of resveratrol.1
The aforementioned study gave mice 22mg of resveratrol per kilogram of body mass per day. That is equivalent to about 1500mg per day for a 150-pound person; other studies have used even higher levels.
However, a new study, funded by the National Institutes of Health, has found a similar benefit to (mouse) life expectancy at much lower levels than these previous studies examined. This NIH-funded study gave the mice 4.9mg of resveratrol per kilogram of body mass per day. This is equivalent to 334mg per day for a 150 pound person.2 Researchers believe that resveratrol extends life in much the same way that calorie restricted diets do, by activating the body at a genetic level to produce Sirtuin 1, an enzyme involved in cellular regulation.
In this new study, the University of Wisconsin-based researchers divided "middle-aged" mice (14 months old) in to one of three treatments. The control group received a normal diet (84 calories per week), the normal diet plus 4.9mg/kg of resveratrol daily, or a calorie restricted diet (63 calories per week, 25% fewer than "normal"). The mice were followed until "old age," 30 to 31 months old. The researchers found that in both resveratrol-treated mice and the calorie-restricted mice there were significant inhibitions in the gene profiles associated with cardiac and skeletal muscle aging, and those which "prevent age-related cardiac dysfunction." There was altered gene expression in 92% of the mice given the resveratrol and 90% of the mice who had the calorie-restricted diet. The resveratrol-treated mice also mimic the effects of the calorie restricted diet on insulin-mediated glucose uptake in muscles. The researchers stated that these findings are associated with a prevention in age-related decline of heart function.
The researchers concluded "our studies suggest that dietary consumption of a low dose of resveratrol partially mimics [caloric restriction] and inhibits some aspects of the aging process." Learn more about this exciting antioxidant and read about additional recent research on resveratrol.
1. Baur, J. A., K. J. Pearson, et al. (2006). "Resveratrol improves health and survival of mice on a high-calorie diet." Nature 444(7117): 337-42.
2. Barger JL, Kayo T, Vann JM, Arias EB, Wang J, et al. (2008) A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice. PLoS ONE 3(6): e2264 doi:10.1371/journal.pone.0002264